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Perspectives on the Human Genome Project and Genomics: Contents

Perspectives on the Human Genome Project and Genomics
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Notes

table of contents
  1. Cover
  2. Half Title Page
  3. Series List
  4. Title Page
  5. Copyright Page
  6. Contents
  7. Preface
  8. List of Abbreviations
  9. Introduction: Complexity, Contingency, and Controversy in Genomics
  10. Part 1. Producing the Genome
    1. 1. Challenges in the Early Years of the Human Genome Project at the National Institutes of Health: A Personal Retrospective
    2. 2. Unsung Contributors to the Human Genome Project: NIH Staff and Advisors
    3. 3. The NHGRI Genome Sequencing Cost Curve: An Indicator of Scientific Progress
    4. 4. History of the Encyclopedia of DNA Elements (ENCODE) Project
    5. 5. NHGRI Genetic Variation Program
    6. 6. Genome Technology Development Grants for the Human Genome Project and Beyond
  11. Part 2. Contextualizing the Genome
    1. 7. The Nature of Genomic Publishing
    2. 8. Europe and the Genome: An Overlooked Strategy for a Translational Genomics
    3. 9. Technological Change Driving Scientific Questions: Genomic Sequencing as a Case Study
    4. 10. Addressing Ethical, Legal, and Social Implications (ELSI): Navigating Ongoing Productive Tensions
    5. 11. “Variations on a Theme”: A History of Errors and Polymorphisms in the Human Genome Project and Beyond
    6. 12. Transforming the Genome into a Clinical Resource: DNA, Data, and Algorithms in Medicine
  12. Part 3. Interpreting the Genome
    1. 13. The Difference Genomics Makes: Characterizing Human Differences After the Human Genome Project
    2. 14. The Trouble with Being “Socially Responsible”: Science, GWAS, and Sexual Orientation
    3. 15. Epigenetics in Public Health: Comments on the “From Cells to Society” Approach
    4. 16. When Eugenic Enhancement Meets the Myth of Genetic Reductionism
    5. 17. modENCODE and the Elaboration of Functional Genomic Methodology
    6. 18. The Cancer Genome Atlas Project: Data-Driven, Hypothesis-Driven, or Something In-Between?
    7. 19. Large-Scale Biology: Philosophical, Historical, and Computational Perspectives
  13. Contributors
  14. Index

Contents

  1. Preface

    Eric D. Green

  2. List of Abbreviations

  3. Introduction: Complexity, Contingency, and Controversy in Genomics

    Christopher R. Donohue and Alan C. Love

  4. Part 1. Producing the Genome

    1. Challenges in the Early Years of the Human Genome Project at the National Institutes of Health: A Personal Retrospective

      Elke Jordan

    2. Unsung Contributors to the Human Genome Project: NIH Staff and Advisors

      Mark Guyer, Kris A. Wetterstrand, and Jane Peterson

    3. The NHGRI Genome Sequencing Cost Curve: An Indicator of Scientific Progress

      Kris A. Wetterstrand and Jonathan E. LoTempio Jr.

    4. History of the Encyclopedia of DNA Elements (ENCODE) Project

      Elise A. Feingold

    5. NHGRI Genetic Variation Program

      Lisa D. Brooks

    6. Genome Technology Development Grants for the Human Genome Project and Beyond

      Jeffery A. Schloss

  5. Part 2. Contextualizing the Genome

    1. The Nature of Genomic Publishing

      Chris Gunter and Magdalena Skipper

    2. Europe and the Genome: An Overlooked Strategy for a Translational Genomics

      Miguel García‐Sancho

    3. Technological Change Driving Scientific Questions: Genomic Sequencing as a Case Study

      Adam L. Felsenfeld and Kris A. Wetterstrand

    4. Addressing Ethical, Legal, and Social Implications (ELSI): Navigating Ongoing Productive Tensions

      Joy Boyer and Jean McEwen

    5. “Variations on a Theme”: A History of Errors and Polymorphisms in the Human Genome Project and Beyond

      Christopher R. Donohue

    6. Transforming the Genome into a Clinical Resource: DNA, Data, and Algorithms in Medicine

      Ramya M. Rajagopalan

  6. Part 3. Interpreting the Genome

    1. The Difference Genomics Makes: Characterizing Human Differences After the Human Genome Project

      Rina Bliss

    2. The Trouble with Being “Socially Responsible”: Science, GWAS, and Sexual Orientation

      Michel Dubois, Catherine Guaspare, and Eric Vilain

    3. Epigenetics in Public Health: Comments on the “From Cells to Society” Approach

      Alexandra Soulier

    4. When Eugenic Enhancement Meets the Myth of Genetic Reductionism

      Sahotra Sarkar

    5. modENCODE and the Elaboration of Functional Genomic Methodology

      Stephan Guttinger and Alan C. Love

    6. The Cancer Genome Atlas Project: Data-Driven, Hypothesis-Driven, or Something In-Between?

      Anya Plutynski

    7. Large-Scale Biology: Philosophical, Historical, and Computational Perspectives

      Emanuele Ratti and Thomas Stoeger

  7. Contributors
  8. Index

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