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Perspectives on the Human Genome Project and Genomics: Part 1 Producing the Genome
Perspectives on the Human Genome Project and Genomics
Part 1 Producing the Genome
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table of contents
Cover
Half Title Page
Series List
Title Page
Copyright Page
Contents
Preface
List of Abbreviations
Introduction: Complexity, Contingency, and Controversy in Genomics
Part 1. Producing the Genome
1. Challenges in the Early Years of the Human Genome Project at the National Institutes of Health: A Personal Retrospective
2. Unsung Contributors to the Human Genome Project: NIH Staff and Advisors
3. The NHGRI Genome Sequencing Cost Curve: An Indicator of Scientific Progress
4. History of the Encyclopedia of DNA Elements (ENCODE) Project
5. NHGRI Genetic Variation Program
6. Genome Technology Development Grants for the Human Genome Project and Beyond
Part 2. Contextualizing the Genome
7. The Nature of Genomic Publishing
8. Europe and the Genome: An Overlooked Strategy for a Translational Genomics
9. Technological Change Driving Scientific Questions: Genomic Sequencing as a Case Study
10. Addressing Ethical, Legal, and Social Implications (ELSI): Navigating Ongoing Productive Tensions
11. “Variations on a Theme”: A History of Errors and Polymorphisms in the Human Genome Project and Beyond
12. Transforming the Genome into a Clinical Resource: DNA, Data, and Algorithms in Medicine
Part 3. Interpreting the Genome
13. The Difference Genomics Makes: Characterizing Human Differences After the Human Genome Project
14. The Trouble with Being “Socially Responsible”: Science, GWAS, and Sexual Orientation
15. Epigenetics in Public Health: Comments on the “From Cells to Society” Approach
16. When Eugenic Enhancement Meets the Myth of Genetic Reductionism
17. modENCODE and the Elaboration of Functional Genomic Methodology
18. The Cancer Genome Atlas Project: Data-Driven, Hypothesis-Driven, or Something In-Between?
19. Large-Scale Biology: Philosophical, Historical, and Computational Perspectives
Contributors
Index
About This Text
Part 1
Producing the Genome
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